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Lanolin comes under focus as a contact allergen

Time : 21st of March 2023 09:46:30 AM Dermatology

Although lanolin and its derivatives are commonly used in cosmetics, its allergenicity remains controversial as a patch test for detecting it is also disputed. Researchers describe it as a weak sensitizer, but it could greatly concern people with dermatitis, leg ulcers, atopic dermatitis, the elderly, and kids. They also call for newer accurate tests to detect lanolin allergy.
  Practical Dermatology

Why is eczema itch so intense?

Time : 2nd of March 2023 01:16:47 PM Physician/Medicine,Dermatology

The itching caused due to eczema is severe as it involves multiple pathways and their malfunctioning. The "neurotic itch" from eczema is caused by nerves that transmit signals from the skin to the brain, while the "psychogenic itch" originates in the brain. Also, the skin damage from eczema promotes bacterial overgrowth and immune responses causing the inappropriate itch.
  Cleveland Clinic

FDA expands the indication of abrocitinib

Time : 14th of February 2023 09:54:30 AM Pharma News,Paediatrics,Dermatology

CIBINQO® (abrocitinib) can now be used among adolescents aged between 12 to 18 years with moderate-to-severe refractory atopic dermatitis, which does not respond to systemic drugs like biologics or in adolescents who cannot take biologics. The once-daily oral drug significantly improved skin clearance, itch, and disease severity after 2 weeks in clinical trials.

EU grants approval for Dupixent to use in children aged 6 months

Time : 1st of February 2023 09:41:31 AM Pharma News,Paediatrics,Dermatology

The European Union's drug regulator granted a new stage of approval for the drug to treat severe atopic dermatitis in children as young as 6 months. Dupixent received approval from the FDA for use in the same age group in June 2022. The drug is developed by Regeneron and Sanofi. The EU's final approval is pending as this indication is in the investigational stage.
  Twitter @Reuters_Health

Study reveals unique signs of monkeypox infection

Time : 24th of January 2023 11:07:41 AM Physician/Medicine,Nursing,Dermatology

A study that analyzed 101 cases from 13 countries revealed that about 54% of patients had skin lesions as the initial sign of infection. About 20% had only one lesion, while 72% had less than 5 lesions suggesting the need for clinical suspicion in high-risk people presenting with lesions. Residual scarring was seen in 13% of cases. About 21% of patients needed hospitalization.
  Twitter @sonya_prasad

A manicure leads to a skin cancer diagnosis in a woman

Time : 19th of January 2023 09:58:43 AM Oncology,Diagnostics & Pathology,Dermatology

A woman in her early 50s got a deep cut on the cuticle during a manicure session, which did not heal properly despite antibiotics. She developed a wart in that area. Dermatologists suggested a biopsy, which revealed an unusual human papillomavirus-related squamous cell carcinoma. Doctors performed Mohs surgery to remove all cancer. She did not require radiation.

AAD issues guidelines for managing atopic dermatitis

Time : 16th of January 2023 01:16:02 PM Dermatology

These guidelines are an update to the 2014 guideline. It has 11 recommendations for managing atopic dermatitis with topical therapies. These recommendations included therapies available like moisturizers, topical calcineurin inhibitors, topical corticosteroids, and topical PDE-4 and JAK inhibitors. They advise against topical antihistamines, antiseptics and antimicrobials.
  American Academy of Dermatology Association

Vitamin D supplements can lower the risk of melanoma

Time : 13th of January 2023 10:28:47 AM Oncology,Nutrition & Fitness,Dermatology

People who regularly used vitamin D supplements were at more than 50% lower risk of melanoma compared to those who did not use the supplements, as per a study. Moreover, regular supplementation was associated with less aggressive forms of melanoma. The study looked at serum levels of calcidiol, melanoma risk, and vitamin D supplementation in the study participants.
  Pharmacy Times

Early initiation of propranolol is beneficial in infantile hemangioma

Time : 11th of January 2023 12:30:51 PM Paediatrics,Dermatology

Initiating oral propranolol at a dose of 3 mg/kg/day before the age of 10 weeks was linked to better treatment success than initiating the treatment after 10 weeks of age (80% vs 60%), according to a study. Researchers suggested that early initiation of treatment could also lower the risk of complications like ulceration and functional consequences.

Skin care products for infants may not prevent food allergies or eczema

Time : 5th of January 2023 09:45:35 AM Pharma News,Paediatrics,Dermatology

Interventions like emollients during infancy did not change the risk of eczema during the initial 1-3 years of life, as per a review study. A few studies also reported that some interventions did not alter the time to develop eczema in children. A study even reported that they might slightly heighten the risk of parents reporting a common food allergen at 2 years of age.