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FDA approves a new PET agent for prostate cancer imaging
POSLUMA® (flotufolastat F18), developed by Blue Earth Diagnostics, is the prostate-specific membrane antigen with multiple indications in PET imaging for men with PSMA-positive lesions and suspected metastasis. It can also be used for men with suspected recurrence based on higher PSA levels. It demonstrated precision even at low PSA levels, with an 83% overall detection rate.
Diagnostic Imaging
WHO warns against misinformation on using AI in healthcare
It advised clinicians to be aware that data used by artificial intelligence in healthcare settings could be inaccurate, misused, and biased. It can lead to the generation of disinformation. It is critical to evaluate the risks of using tools like ChatGPT to protect public health. But, it is also enthusiastic about AI's potential in improving decision-making and diagnosis.
The Print
FDA expands MRI options for Eterna SCS system
Eterna spinal cord stimulation system was previously approved for chronic pain. Its uses are now expanded to include new leads that were magnetic resonance conditional. It can be used with TotalScan MRI technology to provide full-body MRI with normal operating mode scanning and select leads to accelerate imaging and reduce scan time by 50% without safety issues.
NS Medical Devices
Women should start mammograms at 40, not 50, says USPSTF
The new draft recommendations suggest that women initiate breast cancer screening mammograms at the age 40 years instead of 50 years. This advice applies to those assigned females at birth. In contrast, the American Cancer Society recommends that women aged 40 to 44 years at average risk can start screening, but it advises against screening women until age 45 years.
NPR
Repeated CT scans in children could increase cancer risk
Individuals exposed to 4 or more CT scans before the age of 18 years were at a higher risk of developing leukemia, non-Hodgkin lymphoma, and intracranial tumors, as per a study. People who had 2 to 3 CT scans were at higher risk of intracranial tumors but not lymphoma or leukemia. On the other hand, people who underwent just one scan were not at an increased risk of cancer.
Cancer Therapy Advisor
Can the shape of the heart predict heart disease?
A machine learning-based study revealed that roundness or sphericity of the heart is more common than believed earlier. Moreover, it could be a genetic indicator for 47% higher chances of developing cardiac issues for up to 10 years in the future. Intrinsic damage to the heart muscle is believed to trigger sphericity in the left ventricle of the heart even before heart disease.
Stanford Medicine
Ultrasound ablation of global pallidus can improve motor symptoms of Parkinson's
The proportion of patients with Parkinson's disease receiving levodopa who had a reduction of motor impairment or dyskinesia was two times higher in the group which received focused ultrasound ablation therapy of the global pallidus interna than in the group that received a sham procedure, as per a study. Dysarthria and visual and gait disturbances were common side effects.
Twitter @NEJM
Renal denervation lowers systolic blood pressure
Patients with hypertension who were not on antihypertensives and underwent renal denervation reduced daytime ambulatory systolic BP by 7.9 mm Hg compared to 1.8 mm Hg in those who underwent a sham procedure, as per a study. The ultrasound renal denervation effects were consistent throughout a 24-hr circadian cycle. Moreover, 6 out of 7 secondary outcomes also improved with it.
Health Day
A powerful MRI pinpoints the spot in the brain causing seizures
A woman diagnosed with epilepsy at age 11 has suffered seizures for years. Numerous PET, MRI, and ECG scans could not find the problem. A 7-tesla MRI, an FDA-approved scan, revealed a small lesion in the brain. After the non-invasive test pinpointed the tiny lesion, she underwent laser ablation therapy to remove that spot. She remained seizure free after the procedure.
Cleveland Clinic
Gadolinium in MRI contrast agents can infiltrate kidneys
The contrast agents given as infusion to enhance MRI scans contain a rare earth element called gadolinium. Researchers found it could leech from the contrast agent and enter kidney tissues to start nephrogenic systemic fibrosis, which can be fatal. But how the metal detaches from the contrast agent and why only some people develop kidney events is not known.
University of New Mexico
