This site is intended for healthcare professionals
Woman gives birth to a healthy boy post-uterus transplantation
The woman became the first person without a uterus to give birth after uterus transplantation outside a clinical trial. She had Mayer-Rokitansky-Küster-Hauser syndrome, which meant she could never carry her own child. She received a deceased donor uterus transplant and embryo implantation after several months. She gave birth via a planned cesarean section.
CBS News
FDA approves new chemotherapy for endometrial cancer
Dostarlimab-gxly (Jemperli) got approval to be used in combination with paclitaxel and carboplatin, followed by dostarlimab-gxly for treating recurrent and advanced endometrial cancer, which is microsatellite instability-high, or mismatch repair deficient, tested positive on an FDA approved test. It was granted breakthrough and priority review designations.
FDA
COVID-19 boosters do not raise the risk of miscarriages
Data analysis of 100,000 pregnancies prior to 20 weeks gestation showed that only 4% of pregnant women who had spontaneous abortions received a third COVID-19 vaccine or booster shot within 28 days of abortion. These findings were consistent across the mRNA vaccines from Pfizer and Moderna. These findings support the safety of booster vaccines during early pregnancy.
US News
A test to identify pregnancy-related complications receives FDA approval
Thermo Fisher Scientific Inc's biomarker test can help identify women at an increased risk of severe preeclampsia. It is the first-of-its-kind test, which can help reduce mortality from the leading cause during pregnancy in women across the world. This test will have a remarkable impact on the prognosis and treatment of women during pregnancy and postpartum.
US News
Dietary fibre could help avoid gestational diabetes
Pregnant women who took 24 g of dietary fibre powder every day after 20 weeks gestation had lower rates of gestational diabetes than pregnant women in the control group (11.2% vs 23.7%), as per a study. Additionally, the rates of preterm birth were lower in the women taking fibre (12.3% vs 9.4%). Post-prandial sugar levels were also lower in the women taking fibre.
Twitter @RS_Preprints
FDA experts advise RSV shots for pregnant women
This recommendation was unanimous after a large study showed that Pfizer's RSV vaccine was 82% effective in preventing severe RSV in newborns till 3 months old when given to pregnant mothers in the second or third trimester. The 2-dose shot was 69% effective against the infection at 6 months of age. Experts voted 10-to-4 for the safety as it slightly raised preterm birth risk.
CIDRAP
FDA approves new treatment for managing hot flashes
Veozah (fezolinetant) is an oral drug for treating moderate to severe hot flashes in women due to menopause. It is the first neurokinin 3 receptor antagonist that plays a role in regulating body temperature through the brain. It comes with a warning of elevated liver enzymes or damage. Patients using this drug should be monitored for liver damage.
FDA
Can PCOS affect the future generation of men's health?
Sons of women suffering from polycystic ovary syndrome are at double the risk of developing obesity, as per a study. They also had high levels of bad cholesterol, which raises the chances of insulin resistance and, in turn, type 2 diabetes in the future. These findings were also confirmed in studies on mice, highlighting the hidden risks of PCOS.
Karolinska Institutet
WHO: 13.4 million preterm births reported in the last ten years
About one million of these babies died from preterm complications. The report reveals that one in ten births is preterm, and one of these preterm babies dies every 40 seconds. But the rate of preterm births did not change in the last decade. Various agencies raised the alarm against this "silent emergency" to increase the progress in improving children's survival and health.
World Health Organization
Women should start mammograms at 40, not 50, says USPSTF
The new draft recommendations suggest that women initiate breast cancer screening mammograms at the age 40 years instead of 50 years. This advice applies to those assigned females at birth. In contrast, the American Cancer Society recommends that women aged 40 to 44 years at average risk can start screening, but it advises against screening women until age 45 years.
NPR
