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Guidelines on the management of cirrhosis-related bleeding and thrombosis: EASL

Time : 28th of June 2022 02:56:42 PM Physician/Medicine,Gastroenterology

The clinical guidelines by EASL were developed to provide recommendations on the need for coagulation system abnormalities and thrombocytopenia in patients undergoing invasive procedures, views on haemostasis in liver disease and the need for thromboprophylaxis in inpatients with haemostatic abnormality. The guidance is based on panel interventions in clinical practice.
  Twitter @ELSgastro

CDC issues new details on the unknown cause of hepatitis in children in the US

Time : 28th of June 2022 01:01:15 PM Physician/Medicine,Paediatrics,Gastroenterology,Covid-19

About 296 children were diagnosed with mysterious hepatitis in the US between October 1, 2021, and June 15, 2022, while 11 kids died and 18 required liver transplants. Among the diagnosed kids, 44.6% were positive for adenovirus, and 10.2% of kids were positive for COVID-19. About 26% had COVID-19 history, and hepatitis started 133 days, on average, after COVID-19 diagnosis.
  Daily News Kit

ACG/CAG issues guidelines on anticoagulants and antiplatelets during GI bleeding

Time : 27th of June 2022 02:54:14 PM Physician/Medicine,Gastroenterology

These guidelines suggest avoiding administering vitamin K or fresh frozen plasma for hospitalised patients with acute gastrointestinal (GI) bleeding who are taking warfarin. Idarucizumab should be avoided in patients who are on dabigatran therapy. Prothrombin complex concentrate and platelet transfusions should not be given to patients taking direct oral anticoagulants.
  Twitter @AmJGastro

Researchers develop a simple blood test to predict the risk of liver cancer

Time : 27th of June 2022 12:58:07 PM Oncology,Gastroenterology,Diagnostics & Pathology

Identifying the protein levels in the blood samples of NAFLD patients could detect the patients who should be closely monitored for liver cancer. The new test noninvasively identifies the patients who should be followed closely with regular ultrasounds. Most proteins and genes that predict liver cancer risk are inflammatory and immune molecules.
  UT Southwestern Medical Center

AGA issues guidelines on a treatment regimen for patients with IBS

Time : 24th of June 2022 02:48:17 PM Gastroenterology

The guidelines for the first tie outline a treatment plan for patients with irritable bowel syndrome (IBS) with diarrhoea and IBS with constipation. It offers recommendations on when to rely on newly approved drugs, FDA-approved drugs, and over-the-counter drugs. It also provides a framework for targeted therapy strategies for patients with specific symptoms.

Growth hormone could improve liver health in patients with NAFLD

Time : 23rd of June 2022 09:10:20 AM Physician/Medicine,Gastroenterology,Endocrinology & Diabetes

Growth hormone improved hepatic health in people with nonalcoholic fatty liver disease (NAFLD) by reducing liver inflammation and fat, as per a study. Low growth hormone levels and high body weight were related to increased rates of NAFLD and nonalcoholic steatohepatitis. Growth hormone was safe and well-tolerated in patients with hepatic impairment.
  The Endocrine Society

Ustekinumab and Adalimumab work equally well in treating Chron's disease

Time : 22nd of June 2022 08:40:36 AM Physician/Medicine,Pharma News,Gastroenterology

Adalimumab and ustekinumab monotherapies showed no significant safety and efficacy differences in treating biologic-naive patients with moderate to severely active Crohn's disease, according to a study. Both the drugs showed similar rates of clinical remission in patients with Crohn's disease who were resistant or intolerant to conventional therapies.
  Twitter @IcahnMountSinai

FDA approves Risankizumab-rzaa for the treatment of Crohn's disease in adults

Time : 21st of June 2022 11:28:19 AM Physician/Medicine,Pharma News,Gastroenterology

Risankizumab-rzaa (Skyrizi) is the first specific IL-23 inhibitor that received approval for treating moderate to severe active Crohn's disease. Dosing of Skyrizi is 600 mg IV over at least 1 hour at weeks 0, 4 and 8 followed by 36 mg subcutaneous injection at week 12 and every 8 weeks later. Side effects related to Skyrizi are allergic reactions and infections.

How do diet-microbiome interactions affect the physiological effects of diet?

Time : 20th of June 2022 02:00:32 PM Nutrition & Fitness,Gastroenterology

Whole plant foods provide dietary fibres and phytochemicals that promote health by biotransformation by gut microbiota, as per a study. Also, fatty fish, low fat and fermented dairy products provide many dietary components that are beneficial to health by interacting with gut microbiota. In contrast, processed foods elicit their negative effects on the gut environment.
  Twitter @EricTopol

Larger beer with or without alcohol helps gut microbes in men: Study

Time : 20th of June 2022 10:18:08 AM Nutrition & Fitness,Gastroenterology

Men who drank 11 fluid ounces of either non-alcoholic or alcoholic larger beer for four weeks showed higher bacterial diversity in the gut microbiome. Also, they had increased faecal alkaline phosphate levels indicating an improvement in their intestinal health. However, researchers recommended that non-alcoholic beer could be a healthier choice.
  American Chemical Society