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Dapagliflozin can lower hospitalizations in kidney patients

Time : 8th of December 2022 12:07:15 PM Nephrology,Endocrinology & Diabetes

Patients with chronic kidney disease with or without type 2 diabetes and with a urinary albumin-creatinine ratio of 200 to 5,000 mg/g, eGFR of 25 to 75 mL/min/1.73 m2 were treated with dapagliflozin or placebo in a study. The drug reduces the chances of hospitalization in these patients compared to a placebo. This benefit was seen regardless of the presence of diabetes.
  Physician's Weekly

COVID-19 may not increase type 1 diabetes risk in children

Time : 6th of December 2022 11:09:11 AM Paediatrics,Endocrinology & Diabetes,Covid-19

A study conducted on children in Denmark did not find a higher risk of first-time diagnoses of type 1 diabetes in kids 30 days or more following a positive COVID-19 test compared to that in kids without a history of COVID-19. These findings suggest that a special focus on type 1 diabetes after COVID-19 infection in children might not be required.
  Twitter @TracyBethHoeg

A new material to heal diabetic wounds faster

Time : 1st of December 2022 12:11:15 PM Physician/Medicine,Pharma News,Endocrinology & Diabetes

Researchers discovered a polymer that can instruct immune and fibroblast cells to help heal hard-to-treat diabetic wounds. The polymer can be applied directly to diabetic wounds. A single application of this polymer to the wounds in animal models increased fibroblast activity by three times in just four days and caused 80% wound closure, as per the study.
  University of Nottingham

TikTok trend causes a shortage of a diabetes medication

Time : 1st of December 2022 10:34:19 AM Physician/Medicine,Pharma News,Nutrition & Fitness,Endocrinology & Diabetes

Ozempic is a weekly injection that will help patients with type 2 diabetes improve their insulin sensitivity and suppress appetite, causing weight loss. Some celebrities started using it to shed weight, which sparked people's interest. Now the demand for this drug is causing shortages and harm to needy patients. Another weight loss drug Wegovy's supply also reduced.
  USA Today

The first drug for delaying type 1 diabetes onset gets FDA approval

Time : 21st of November 2022 09:33:15 AM Physician/Medicine,Pharma News,Paediatrics,Endocrinology & Diabetes

Tzield (teplizumab-mzwv) has been approved for use in adults and children aged 8 years and above for delaying the onset of stage 3 T1D. The drug can be used for people currently suffering from stage 2 T1D. The drug is believed to deactivate immune cells that attack pancreatic cells that produce insulin. It can be given as an IV infusion once daily for every 14 days.

Some low-carb diets may increase the risk of diabetes

Time : 18th of November 2022 11:36:58 AM Physician/Medicine,Nutrition & Fitness,Endocrinology & Diabetes

A study finds that an animal-based low-carbohydrate diet is linked to a 35% higher risk of type 2 diabetes and a 39% higher risk if the diet limits whole grain intake. In contrast, a plant-based low-carbohydrate diet was linked to a 6% lower risk of diabetes and a 15% lower risk if the diet limited sugar and refined carbohydrates. These findings may vary across ethnic groups.
  American Heart Association

A review weighs the risks and benefits of pancreas transplantation for diabetes

Time : 16th of November 2022 10:56:00 AM Physician/Medicine,General Surgery,Endocrinology & Diabetes

Pancreas transplantation can benefit patients with type 1 diabetes in managing their insulin and blood glucose levels. But, patients should take immunosuppressants with side effects for a lifetime to avoid graft rejection. Moreover, the median graft survival time is only about 8 years. But, a combined kidney/pancreas transplant may benefit diabetics with kidney disease.

Artificial night lights linked to increased prevalence of diabetes

Time : 16th of November 2022 10:01:57 AM Physician/Medicine,Nutrition & Fitness,Endocrinology & Diabetes

People exposed to the highest amount of artificial night lights or outdoor artificial light at night in a study had a 28% increased prevalence of diabetes compared to those exposed to the lowest amounts of lights at night. Chronic exposure to night lights was also associated with higher blood glucose levels, lower beta cell function, and insulin resistance.
  Verve Times

Subclinical hyperthyroidism tied to fracture risk

Time : 10th of November 2022 10:18:44 AM Physician/Medicine,Orthopaedics,Endocrinology & Diabetes

People with subclinical hyperthyroidism were associated with a 34% increased risk of fractures compared to patients with euthyroidism, as per a study. The fracture risk was higher among patients with thyrotropin levels below 0.56 mIU/L. These findings suggest the need for aggressive screening and monitoring for bone mineral disease in people with subclinical hyperthyroidism.
  Twitter @JAMANetworkOpen

HbA1c in people with prediabetes can predict cardiovascular risk

Time : 7th of November 2022 11:37:59 AM Endocrinology & Diabetes,Diagnostics & Pathology,Cardiology

Prediabetes, which is defined as HbA1c levels ranging from 6 to 6.5 as per the International Expert Committee, is linked to an increased risk of major adverse cardiovascular events than normal glucose tolerance tests, as per a study. These findings could help physicians identify patients at high risk of cardiovascular events and provide early lifestyle intervention.
  Twitter @RS_Preprints