Death toll due to COVID-19 could be much higher if vaccines were not available
COVID-19 would have led to over 100,000 additional cases in 2021 if the effective vaccines against SARS-CoV-2 were unavailable, as per the Pfizer analysis. Also, it revealed that, in 2021, Pfizer jabs alone had saved over 110,000 lives. Experts stated that the analysis was significant as it is essential for Americans to understand the importance of vaccines.
ABC News
A case of an emphysematous aortitis
A 74-year-old man presented to an emergency department with reduced responsiveness during hemodialysis. A chest radiograph showed a widened mediastinum. Based on clinical and lab findings, the patient was diagnosed with emphysematous aortitis, and he was treated with intravenous clindamycin and penicillin G. However, the patient died on day 7 of hospitalisation.
Twitter @NEJM
AACE issues guidelines for NAFLD management to endocrinology and primary care
The new recommendations on NAFLD are the first to be specifically targeted at endocrinology and primary care settings. It includes 34 evidence-based clinical practice recommendations for diagnosis, screening and referrals, which are presented in a table, algorithm flow chart and detailed text. The recommended screen test for high-risk patients is the fibrosis-4 index.
Health News
FDA has refused to approve a common antidepressant to treat COVID-19
FDA declined to authorise fluvoxamine as COVID-19 treatment, stating that it was not shown to be effective against the virus. The agency determined that the data from the available evidence are insufficient to conclude that the drug may effectively manage COVID-19 in non-hospitalised patients and prevent the progression of hospitalisations or severe disease.
US News
Biological E has reduced the price of Corbevax by 70% for the private market
Biological E Limited reduced the Corbevax price of each dose to INR 250 ($3.23) inclusive of taxes. It reduced the price to make vaccines affordable and help to boost the protection of the maximum number of children. Currently, the end-users are required to pay INR 400 ($ 5.16) for each dose at a private vaccination centre, which includes administration charges.
Business Standard
FDA approves a dual-targeting treatment for people with type 2 diabetes
Mounjaro (tirzepatide) injection was approved to enhance blood sugar control, as an addition to exercise and diet, in adult patients with type 2 diabetes. It was more effective than other diabetes treatments such as GLP-1 receptor antagonist, two long-acting insulin analogues and a placebo, as per a trial. Common adverse events were nausea, diarrhoea, and vomiting.
FDA
Nurse sentenced to 3 years of supervised probation after a patient's death
Former nurse RaDonda Vaught was found guilty when her 75-year-old patient died after being given a paralysis drug instead of a sedative in 2017, and she was given prison of eight years. However, Judge diverted the sentence and removed all charges from her record. Although the prosecution argued that charges should not be diverted, but did not oppose the probation sentencing.
Daily Mail
Playing video games could help in boosting the child's intelligence
The children who played more games than the average had greatly improved their intelligence by nearly 2.5 IQ points more than an average, as per a study. However, no significant effect was found in children who watched TV or social media. These study findings will support the statement that declared that screen time doesn't impair the cognitive abilities of children.
Karolinska Institutet
Short term ibuprofen use could increase the risk of chronic pain
Drugs used to relieve short term health issues could increase the risk of chronic pain, as per a study. Also, it showed that blocking inflammation with drugs such as ibuprofen and steroids could make it harder to treat the problems. Moreover, a study supported these findings that showed people taking these drugs might experience pain after 2 to 10 years.
The Guardian
FDA approves Onyx Frontier drug-eluting stent
Medtronic Onyx Frontier was invented to leverage the stent platform as Resolute with an advanced delivery system for increasing acute performance and improving deliverability. It is used to treat patients with coronary artery disease. Physicians deliver the sent by a minimally invasive procedure to prop open the artery to treat blockage of arteries.
Drug Delivery business
